Last refreshed: July 21, 2026 (US ET)
Back to holdings

AZN

Defensive

AstraZeneca PLC

Health Care·Drug Manufacturers - General·β 0.28Yield: Mid (1-3%)

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Crestor, Andexxa, Onglyza, Symlin, XIGDUO XR, Atacand, Atacand HCT, Atacand Plus, Farxiga/Forxiga, Plendil, Modip, Splendil, Munobal, Flodil, Tenormin, Tenormine, Prenormine, Atenol, Zestril, Brilinta/Brilique, Komboglyze, Qtern, Wainua, Byetta, Lokelma, Seloken ZOK, Toprol-XL, Betaloc ZOK, XIGDUO, Accolate, Accoleit, Vanticon, Bricanyl Respules, Eklira Genuair/Tudorza/Bretaris, Pulmicort Turbuhaler, Symbicort Turbuhaler, Airsupra, Bricanyl Turbuhaler, Fasenra, Rhinocort, Tezspire, Bevespi Aerosphere, Daliresp/Daxas, Oxis Turbuhaler, Saphnelo, Breztri Aerosphere, Duaklir Genuair, Pulmicort Respules, and Symbicort pMDI.

Close · 3M

-15.61%

AZN · 3M

-15.61%

Pinch / wheel to zoom · drag to pan · double-tap to reset

Held by 1 AI ETF

PQNT1.980%

as of Jul 21

Signal performance

Each tracked ETF's moves on this stock, grouped by fund. Returns are measured from the signal date to the latest close — hypothetical, no commissions or slippage.

Buy signals5
Win rate0% (0/5)
Avg buy return-10.24%
PQNTnow 1.980% of fund14 signals

PQNT · Weight increase · 2d

AstraZeneca (AZN) trades at $168.90, placing it at 81% of its 52-week high, following a -7.1% return over the past 30 days and a -13.4% decline across 90 days, contrasting with a 1-year return of +142.6%. This recent price trajectory, after a period of substantial long-term gains, likely prompted a re-evaluation within PQNT's AI-driven strategy. Pictet's AI system, which integrates factor exposures like valuation, sentiment, and momentum for its international developed-market portfolio, appears to have identified a renewed opportunity in AZN. Following a sequence of reductions, the fund’s consecutive weight increases on 2026-07-17 to 1.9600% and 2026-07-18 to 1.9800% indicate that the AI signals, possibly detecting favorable valuation after the recent pullback or a positive shift in sentiment for the Health Care stock, advocated for expanding the position. Such moves align with a periodic rebalancing approach, where the AI's overlay on fundamental and momentum factors drives adjustments.

weight 1.730% → 1.980% (+0.250 pp)·stock down 5.5% in the 30 days before

Jul 18·entry $164.52·now $164.52Fresh

0.00%
since Jul 18

PQNT · Weight decrease · 2d

The consecutive daily weight decreases for AstraZeneca, moving from 2.09% to 1.73% between July 5th and July 16th, 2026, reflect a measured reduction in exposure by Pictet Asset Management's PQNT. This graduated trimming, rather than an abrupt sell-off, aligns with the fund’s periodic rebalancing schedule and its integration of AI signals with factor exposures. Given AZN's significant +136.7% 1-year return, juxtaposed against its recent -13.3% 90-day return and current price at 80% of its 52-week high, the AI-driven methodology likely flagged a shift in momentum or valuation. The fund's strategy, targeting developed-international stocks ex-US, thus appears to be incrementally adjusting its position in the health care company based on these converging quantitative signals.

weight 1.800% → 1.730% (-0.070 pp)·stock down 4.5% in the 30 days before

Jul 16·entry $169.29·now $164.52

-2.82%
since Jul 16

PQNT · Weight decrease · 3d

AstraZeneca's weighting in PQNT exhibited a clear pattern of consecutive decreases, shifting from a stable 2.09% to 1.80% across several trading days in July, indicating a deliberate, stepped reduction of exposure. This sequential adjustment is consistent with Pictet's AI-managed strategy, which integrates factor exposures like momentum and valuation, likely reacting to AZN's recent 30-day return of -7.4% and 90-day return of -14.9%. Despite a prior one-year return of +145.7%, the AI’s re-evaluation of AZN at its current $171.61, still at 82% of its 52-week high, suggests a recalibration based on evolving signals. The newer fund's periodic rebalancing schedule, rather than daily adjustments, allowed for this methodical reduction of a healthcare position within its broad international developed-market portfolio.

weight 2.090% → 1.800% (-0.290 pp)·stock down 6.4% in the 30 days before

Jul 12·entry $169.47·now $164.52

-2.92%
since Jul 12

PQNT · Weight decrease · 2d

The detected pattern in PQNT's allocation to AstraZeneca reveals a subtle, stepped decrease over two consecutive trading days, specifically reducing weight from 2.09% to 2.01% on July 9th and 10th. This graduated trimming aligns with Pictet Asset Management's AI-driven strategy, which integrates momentum and sentiment signals, as AstraZeneca's price data shows significant recent deterioration. While the health care stock posted a +145.7% 1-year return, its 30-day return of -7.4% and 90-day return of -14.9%, combined with its current price at 82% of its 52-week high, suggest a decline in short-term positive drivers. The AI overlay within this ex-US developed-market fund likely flagged these weakening short-term factors in AZN, prompting a measured, periodic rebalancing decision to reduce exposure rather than an immediate, drastic change.

weight 2.090% → 2.010% (-0.080 pp)·stock down 6.4% in the 30 days before

Jul 10·entry $171.61·now $164.52

-4.13%
since Jul 10

PQNT · Weight decrease · 2d

Pictet Asset Management’s PQNT, which systematically applies AI signals combined with factor exposures across approximately 300 international developed-market stocks, adjusted its weight in AstraZeneca following recent shifts in the company's profile. The fund's consecutive weight decrease for AZN, moving from 2.07% to 2.03% between July 1st and 2nd, indicates its machine learning models likely re-evaluated momentum and valuation signals. Despite a +159.8% 1-year return, AZN's more recent -10.3% 90-day return at its current $183.86 price point could have triggered this periodic rebalancing decision, reflecting the AI's response to an evolving risk-reward assessment.

weight 2.070% → 2.030% (-0.040 pp)·stock up 10.0% in the 30 days before

Jul 2·entry $195.15·now $164.52

-15.70%
since Jul 2

PQNT · Weight increase · 4d

Pictet Asset Management's PQNT, an ETF leveraging AI signals combined with factor exposures across its ~300 international developed-market stocks, systematically increased its allocation to AstraZeneca. The fund's AI overlay prompted a consecutive weight increase for AZN, moving the position from 1.93% to 2.07% between June 24 and June 28, consistent with its periodic rebalancing schedule. This accumulation occurred while AstraZeneca traded at 90% of its 52-week high, indicating the AI's models registered continued positive signals within the healthcare sector. The fund’s broad ex-US developed-market style therefore identified AZN as a strong candidate for a higher weighting despite recent market movements.

weight 1.910% → 2.070% (+0.160 pp)·stock up 1.5% in the 30 days before

Jun 28·entry $190.95·now $164.52Fresh

-13.84%
since Jun 28

PQNT · Weight increase · 3d

AstraZeneca's substantial 1-year return of +153.2% and its current price of $188.41, placing it at 90% of its 52-week high, indicates a strong long-term performance aligning with the momentum and sentiment factors incorporated in PQNT's AI overlay strategy. Managed by Pictet Asset Management, this ex-US developed-market fund sequentially increased its AZN allocation from 1.93% on June 24th to 2.01% by June 26th. This specific weighting adjustment occurred as the stock showed a +1.9% 30-day return, navigating its way out of a -9.7% 90-day period. The AI signals, combined with fundamental and valuation factor exposures specific to this Health Care company, likely detected a re-emerging positive trend within the international universe, prompting the specific additions to its portfolio.

weight 1.910% → 2.010% (+0.100 pp)·stock up 1.5% in the 30 days before

Jun 26·entry $188.41·now $164.52Fresh

-12.68%
since Jun 26

PQNT · Weight increase · 2d

Pictet Asset Management's PQNT, which employs AI signals alongside factor exposures for its approximately 300 international developed-market stocks, recently increased its weight in AstraZeneca (AZN). This upward adjustment, shifting AZN's allocation from 1.91% to 2.00% between June 22 and June 25, 2026, suggests the fund's AI overlay detected a compelling opportunity amidst recent price consolidation. Despite a 90-day return of -11.0% at a current price of $183.02, the AI system, considering factors such as fundamentals or momentum, may view this as a favorable entry point given the company's significant 1-year return of +148.2%. The periodic, rather than daily, rebalancing schedule of this newer fund launched in 2025 indicates these weight changes reflect a considered re-evaluation by the AI and factor models, targeting its broad ex-US developed-market exposure.

weight 1.910% → 2.000% (+0.090 pp)·stock down 0.8% in the 30 days before

Jun 25·entry $185.68·now $164.52Fresh

-11.40%
since Jun 25

PQNT · Weight decrease · 2d

AstraZeneca’s 1-year return of +150.3% has positioned the stock at $182.28, 87% of its 52-week high, following a period of considerable price appreciation. Pictet Asset Management's PQNT, which combines AI signals with valuation and momentum factor exposures within its developed-international universe, registered consecutive weight decreases in AZN from 2.06% on June 8th to 2.01% on June 12th. This systematic reduction aligns with the fund’s AI overlay and factor model identifying a potential shift in momentum or an unfavorable valuation after such a significant climb. The stock’s -2.7% 30-day return and -1.1% 90-day return, preceding and occurring during this rebalancing period, suggest the AI perceived a cooling trend. This managed decrease in exposure reflects the newer fund’s strategy to optimize its circa 300 international developed-market stock holdings in response to changing market signals.

weight 2.060% → 2.010% (-0.050 pp)·stock down 4.8% in the 30 days before

Jun 12·entry $178.75·now $164.52

-7.96%
since Jun 12

PQNT · Weight decrease · 2d

weight 2.010% → 1.960% (-0.050 pp)·stock up 0.3% in the 30 days before

Jun 4·entry $181.80·now $164.52

-9.50%
since Jun 4

PQNT · Weight increase · 2d

The PQNT fund initiated a clear, stepped accumulation of AstraZeneca, incrementally adjusting its weight from 1.9500% to 2.0400% over eight days, punctuated by periods of stability between increases. This rebalancing cadence from Pictet Asset Management suggests the AI overlay, combined with factor exposures, identified AstraZeneca as a compelling non-US developed market asset for its portfolio. Its 90-day return of +100.2% and 1-year return of +41.7% likely provided strong momentum and fundamental signals, leading the fund's models to increase exposure despite a recent 30-day return of -8.6% and a current price of $187.46, which is 89% of its 52-week high.

weight 2.000% → 2.040% (+0.040 pp)·stock down 2.6% in the 30 days before

May 21·entry $189.75·now $164.52Fresh

-13.30%
since May 21

PQNT · Weight decrease · 3d

The AI ETF likely initiated the consecutive weight decrease for AZN after processing a range of data points indicating a deteriorating outlook or an increased risk profile for AstraZeneca. This could include negative news concerning drug trials, regulatory updates, competitive landscape shifts, or a general downturn in healthcare sector sentiment, leading the algorithm to reduce exposure and reallocate capital. For a retail investor, this pattern should serve as a practical alert to conduct immediate and thorough due diligence on AZN and the broader healthcare sector. It emphasizes the importance of actively monitoring investments and being prepared to adjust one's own position based on evolving information, rather than passively holding a stock.

weight 1.990% → 1.930% (-0.060 pp)·stock down 10.8% in the 30 days before

May 10·entry $181.86·now $164.52

-9.53%
since May 10

PQNT · Weight decrease · 2d

The AI ETF's consecutive weight decrease in AstraZeneca suggests its algorithms have identified persistent negative signals, potentially related to fundamental shifts like drug pipeline setbacks, increased competition, or a re-evaluation of its valuation relative to market alternatives. For a retail investor, this action by a sophisticated AI system should serve as a prompt for immediate personal due diligence into AZN's recent news and sector trends, verifying if their own investment thesis remains valid despite the AI's decision to de-risk.

weight 1.990% → 1.950% (-0.040 pp)·stock down 10.8% in the 30 days before

May 8·entry $182.85·now $164.52

-10.02%
since May 8

PQNT · Weight decrease · 2d

The AI ETF is likely de-weighting AZN due to its algorithms detecting weakening momentum, increasing short-term risk, or a programmatic shift away from the healthcare sector's current attractiveness. For retail investors, this consistent reduction suggests the AI sees diminishing relative value or increasing headwinds for AZN, warranting independent research into the company's recent performance or broader sector outlook.

weight 2.080% → 2.010% (-0.070 pp)·stock down 4.5% in the 30 days before

Apr 29·entry $185.20·now $164.52

-11.17%
since Apr 29

Sell signals show what the stock did after the AI exited. A negative number means the AI's exit was well-timed.