Last refreshed: July 21, 2026 (US ET)
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ISRG

Growth

Intuitive Surgical, Inc.

Health Care·Health Care Equipment·β 1.68

Intuitive Surgical, Inc. develops, manufactures, and markets products that enable physicians and healthcare providers to enhance the quality of and access to minimally invasive care in the United States and internationally. It offers the da Vinci Surgical System that enables surgical procedures using a minimally invasive approach; and Ion endoluminal system, which extends its commercial offerings beyond surgery into diagnostic endoluminal procedures enabling minimally invasive biopsies in the lung.

Close · 3M

-28.44%

ISRG · 3M

-28.44%

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Held by 1 AI ETF

PQUS1.080%

as of Jul 21

Signal performance

Each tracked ETF's moves on this stock, grouped by fund. Returns are measured from the signal date to the latest close — hypothetical, no commissions or slippage.

Buy signals2
Win rate0% (0/2)
Avg buy return-7.82%
PQUSnow 1.080% of fund8 signals

PQUS · Weight increase · 2d

Intuitive Surgical, Inc. (ISRG) presents strong financials with 21.43% revenue growth and a 16.98% Return on Equity, alongside a P/E of 41.06 and P/B of 11.26, indicating a growth company that aligns with the US large-cap universe targeted by the Pictet-managed PQUS. The AI ranking system likely identified an opportunity as ISRG’s price dropped to $345.42, its 52-week low, reflecting a 35.4% one-year return and placing it at 58% of its 52-week high around the time of the portfolio adjustment. Despite PQUS's style of measured turnover, the AI algorithm executed a significant increase in ISRG's weight from 0.71% on July 16 to 1.19% on July 17, followed by a consecutive rise to 1.24% on July 18, demonstrating a high-conviction decision to capitalize on the health care stock’s depressed valuation. This move suggests the fund's AI-driven system, which incorporates sector-balance and concentration rules across its ~165 US large caps, perceived a compelling entry point for a fundamentally sound company.

weight 0.710% → 1.240% (+0.530 pp)·stock down 17.2% in the 30 days before

Jul 18·entry $353.17·now $353.17Fresh

0.00%
since Jul 18

PQUS · Sudden change · 1d

Intuitive Surgical's PER of 48.83 and PBR of 11.26, combined with a 21.43% revenue growth and 16.98% ROE, present a profile consistent with a growth-oriented company, a factor Pictet Asset Management's AI ranking system likely assesses within its US large-cap universe. The abrupt increase in PQUS's allocation to ISRG from 0.7100% to 1.1900% on 2026-07-17 aligns with the stock's recent valuation context, trading at $402.33, having experienced a -18.5% return over 90 days and sitting at 68% of its 52-week high. This specific adjustment suggests the AI's periodic rebalancing mechanism determined ISRG's current price offered a more favorable entry point given its underlying financials, leading to a measured increase in position in line with the fund's sector-balance and concentration rules for its portfolio of ~165 US large caps.

weight 0.710% → 1.190% (+0.480 pp)·stock down 17.2% in the 30 days before

Jul 17·entry $345.42·now $353.17

+2.24%
since Jul 17

PQUS · Weight decrease · 3d

Pictet Asset Management's AI ranking system, overseeing its portfolio of approximately 165 US large-cap holdings, appears to have initiated a measured reduction in ISRG's allocation. This consecutive weight decrease, observed from 0.80% down to 0.76% over several days, aligns with the fund's style of measured turnover and periodic rebalances. The AI's evaluation likely flagged ISRG's recent price trajectory, given its 90-day return of -18.2% and the stock currently trading at 69% of its 52-week high. Despite the company's 21.43% revenue growth, the AI's algorithm, within its sector-balance and concentration rules, seems to have prioritized the negative price momentum, triggering this systematic de-allocation. This action suggests a revised ranking for ISRG within the AI's US large-cap universe.

weight 0.800% → 0.760% (-0.040 pp)·stock down 4.6% in the 30 days before

Jul 12·entry $407.12·now $353.17

-13.25%
since Jul 12

PQUS · Weight decrease · 2d

The fund’s recent adjustment to Intuitive Surgical shares involved a fractional, consecutive reduction, moving from a stable 0.8000% to 0.7900% and then 0.7700% over two days. This measured cadence of change aligns with Pictet Asset Management's stated style of US large-cap management with measured turnover, reflecting its periodic rebalances rather than daily shifts. The AI ranking system, applied to ISRG's current price of $406.78—which is near the 52-week low after a -23.8% one-year return—likely re-evaluated its position. Despite 21.43% revenue growth and 16.98% ROE, the stock still carries a PER of 48.83 and PBR of 11.26, indicating a valuation that the AI, even with sector-balance rules, might consider less compelling within its ~165 US large-cap universe given the recent price depreciation. Such small, sequential downward adjustments suggest the AI's internal ranking of ISRG has softened, prompting a gradual recalibration of exposure without triggering a drastic reallocation.

weight 0.800% → 0.770% (-0.030 pp)·stock down 4.6% in the 30 days before

Jul 11·entry $407.12·now $353.17

-13.25%
since Jul 11

PQUS · Weight decrease · 3d

Intuitive Surgical, Inc. (ISRG) currently trades at $411.06, near the lower bound of its 52-week range and down over 10% in the last 30 days, reflecting a year-long decline of over 25%. This sustained downward price trajectory, especially with the stock sitting at 69% of its 52-week high, likely prompted PQUS's AI ranking system to reassess ISRG's position within its US large-cap universe. Despite a 21.43% revenue growth and 16.98% ROE, the company’s high PER of 48.6 and PBR of 11.26, combined with the stock's underperformance, may have flagged it as less appealing by the AI's criteria. This systematic scaling back of exposure resulted in the consecutive weight reductions from 0.81% to 0.79% observed between June 12 and June 14, indicating the manager's periodic rebalancing mechanism, incorporating sector-balance and concentration rules, prioritized trimming this holding in response to the stock's recent market behavior.

weight 0.820% → 0.790% (-0.030 pp)·stock down 4.9% in the 30 days before

Jun 14·entry $416.55·now $353.17

-15.22%
since Jun 14

PQUS · Weight decrease · 2d

ISRG's valuation multiples, with a PER of 48.6 and PBR of 11.26, stand against its 21.43% revenue growth and 16.98% ROE, figures the Pictet AI ranking system likely weighs within its US large-cap universe for PQUS. Despite its solid profitability, the AI's consecutive weight decrease in ISRG from 0.81% to 0.80% between June 10th and June 13th suggests a re-evaluation of its attractiveness, especially given the ETF's "measured turnover" approach. This specific period of declining allocation aligns with ISRG's broader price trend, which shows a -10.2% 30-day return and -25.7% 1-year return, placing the stock near 69% of its 52-week high at $411.06. The AI, managing PQUS with sector-balance and concentration rules, appears to be gradually de-emphasizing ISRG, where the perceived risk from sustained price depreciation combines with its high valuation, overriding the positive aspects of its current growth metrics.

weight 0.820% → 0.800% (-0.020 pp)·stock down 4.9% in the 30 days before

Jun 13·entry $416.55·now $353.17

-15.22%
since Jun 13

PQUS · Weight increase · 2d

weight 0.770% → 0.820% (+0.050 pp)·stock down 6.6% in the 30 days before

Jun 7·entry $418.61·now $353.17Fresh

-15.63%
since Jun 7

PQUS · Sudden change · 1d

Intuitive Surgical currently trades at $423.63, positioned at 71% of its 52-week high and near its 52-week low of $418.55, reflecting a 24.4% return decline over the past year. Pictet Asset Management's AI ranking system likely identified ISRG as an attractive US large-cap within the healthcare sector following its significant price correction. With revenue growth at 21.43% and ROE at 16.98%, alongside a PER of 50.16 and PBR of 11.26, the underlying financials present a specific case for consideration. The sudden upward adjustment on May 29, 2026, increasing the weight from 0.30% to 0.62%, demonstrates the fund's periodic rebalancing mechanism acting on a stock whose valuation has become more appealing in the context of its defined rules. This move aligns with the newer fund's measured turnover style, leveraging a valuation opportunity after the stock's recent market performance.

weight 0.300% → 0.620% (+0.320 pp)·stock down 6.4% in the 30 days before

May 29·entry $424.64·now $353.17

-16.83%
since May 29

Sell signals show what the stock did after the AI exited. A negative number means the AI's exit was well-timed.

Buffett-style framework

Fails the frameworkas of Jul 12

AI ETF PQUS shows a consistent trend of decreasing its weight in Intuitive Surgical, signaling a reduction in its holding. This selling activity aligns with the framework's 'Fail' verdict, which finds the current valuation unattractive despite the company's strong business fundamentals.

  • Circle of CompetenceIntuitive Surgical's business model, based on a growing installed base and recurring procedure-driven revenue, offers predictable unit economics suitable for long-term cash flow projections.
  • Economic MoatThe company possesses a strong economic moat due to high switching costs for hospitals, significant intangible assets like brand and patents, and a powerful ecosystem effect from its dominant installed base.
  • ManagementInformation regarding management's candor, capital allocation discipline, or skin in the game is not provided, preventing an assessment of this stage.
  • Financial HealthWhile the current ROE is strong, insufficient data on 10-year ROE stability, operating margins, debt structure, and owner earnings prevents a conclusive pass on financial health criteria.
  • Margin of SafetyThe current valuation multiples, including a PER of 48.83 and EV/EBITDA of 51.0, are exceptionally high, leaving no defensible margin of safety for a conservative investor.

Intuitive Surgical operates within a predictable circle of competence and is protected by a strong economic moat, making it a wonderful business. However, critical financial health data was not available to fully assess its long-term financial stability, and the current valuation offers no margin of safety. Therefore, a value-investing framework would currently deem it uninvestable at its current price.

Educational interpretation generated by AI applying frameworks Warren Buffett documented in his shareholder letters and other public writings. Not a statement by Mr. Buffett or Berkshire Hathaway, and not investment advice.